What Is Tipranavir?
Tipranavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.
Tipranavir is used together with another drug called ritonavir to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).Tipranavir is not a cure for HIV or AIDS.
Tipranavir may also be used for purposes not listed in this medication guide.
You should not use tipranavir if you have moderate to severe liver disease.
Tell your doctor about all your current medicines and any you start or stop using.Many drugs can interact, and some drugs should not be used together.
Some people taking tipranavir with ritonavir have developed fatal medical problems including liver damage and bleeding in the brain.Stop taking these medicines and get emergency medical attention if you have: right-sided upper stomach pain, nausea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), unusual bleeding, sudden severe headache, or problems with speech or vision.
You should not use tipranavir if you are allergic to it, or if you have:
- moderate to severe liver disease.
Some medicines can cause unwanted or dangerous effects when used with tipranavir.Your doctor may change your treatment plan if you also use:
- sildenafil (Revatio for pulmonary arterial hypertension);
- St. John's wort;
- ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine;
- heart medication--amiodarone, flecainide, propafenone, quinidine;
- a sedative--oral midazolam, triazolam; or
- "statin" cholesterol medicine--atorvastatin, lovastatin, simvastatin.
Tell your doctor if you have ever had:
- liver disease (especially hepatitis B or C);
- high cholesterol or triglycerides;
- a bleeding disorder such as hemophilia; or
- an allergy to sulfa drugs.
Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.
Tipranavir can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Tipranavir should not be given to a child younger than 2 years old.
Tipranavir Side Effects
Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some people taking tipranavir with ritonavir have developed fatal medical problems including liver damage and bleeding in the brain.Stop taking this medicine and get emergency medical attention if you have:
- right-sided upper stomach pain, nausea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- unusual bleeding, sudden severe headache, problems with speech or vision.
Call your doctor at once if you have:
- severe skin rash, blistering, peeling, redness or sunburn;
- skin rash and also joint or muscle pain, fever, or tightness in your throat; or
- increased thirst, increased urination, hunger, dry mouth.
Tipranavir affects your immune system, which may cause certain side effects (even weeks or months after you've taken this medicine). Tell your doctor if you have:
- signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
- trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
- swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.
Common side effects may include:
- nausea, vomiting, diarrhea, stomach pain;
- skin rash (especially in children);
- headache, fever, tired feeling; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Tipranavir is taken in combination with ritonavir (Norvir). Use tipranavir and ritonavir regularly to get the most benefit.
Take your medicine with food if you take tipranavirwith ritonavir tablets.
You may take your medicine with or without food if you take tipranavirwith ritonavir capsules or liquid.
Swallow thetipranavir capsulewhole. Do not break or chew it.
Measuretipranavir liquidcarefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Tell your doctor if the child using this medicine has any changes in height or weight. Tipranavir doses are based on body surface area (height and weight) in children, and any changes may affect your dose.
You will need frequent medical tests.
If you need surgery, tell the surgeon ahead of time that you are using tipranavir.
Use all HIV medications as directed and read all medication guides you receive.Do not change your dose or dosing schedule without your doctor's advice.Every person with HIV should remain under the care of a doctor.
Store an unopened bottle of tipranavircapsulesin the refrigerator. Do not freeze.After opening the bottle, store the capsules at room temperature.
Store tipranavirliquidat room temperature away from moisture and heat.Do not store the liquid in the refrigerator.
Throw away any capsules or liquid you have not used within 60 days after you first opened the medicine bottle.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.
Get your prescription refilled before you run out of medicine completely.
Copyright 1996-2019 Cerner Multum, Inc.
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